I have been taking New Chapter SJW for the past year or so on a regular basis. I've had good results and it has been consistently effective. However, today I went in for a through eye exam due to a history of Glacoma in my family. What they found was good eye pressure (no Glacoma) but the beginning of cataracts in both eyes. The eye Doc was a bit surprised as at my last exam about a year and 1/2 ago, there were no signs of cartaracts. I know this could just be the result of aging, but in light of several studies that show an elevated risk of cataracts in long term SJW users, I think it's time to stop and try something else like SAM-e. If you've been using SJW for a long time, it might be a good idea to get your eyes checked just to be on the safe side.